Home » Products » L-NORVALINE 99%


Synonyms: H-Nva-OH , L(+)-Norvaline , (S)-2-Aminopentanoic acid , (S)-(+)-Norvaline
CAS Number: 6600-40-4
Boiling Pt: 228 °C (1013 hPa)
Formula: C₅H₁₁NO₂
EINECS: 229-543-3





L-norvaline is a non-essential amino acid and an isomer of the branched-chain amino acid (BCAA) valine. Isomers share the same number of atoms and molecules of each element component but have distinct arrangements. Unlike valine, l-norvaline is an unbranched-chain amino acid. It’s a common ingredient in pre-workout supplement stacks due to its interactions with arginine. Recent research also shows that l-norvaline has neuroprotective properties that may support long-term cognitive health.

Nutrition Facts:

Other Ingredients: None

Free of:  Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives.

Directions:  As a dietary supplement, take 400 mg (3/16 tsp) daily, or as directed by a physician. Accurate gram weight scale recommended.

Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children. Store in a cool, dark & dry place.



L-Norvaline may enhance athleticism by inhibiting arginase enzymes. These enzymes break down arginine into l-ornithine and urea as part of the urea cycle to remove ammonia buildup. However, arginase competes with nitric oxide synthase (NOS) enzymes for arginine. Arginase also has more than 1000 times the activity of NOS enzymes. NOS enzymes are essential for nitric oxide synthesis, and too much arginase can create a nitric oxide deficiency.

By inhibiting arginase, l-norvaline helps preserve arginine levels to use for nitric oxide production. One study found that norvaline boosted nitric oxide production by 55%. Nitric oxide is a vasodilator that improves blood flow, relaxes blood vessels, and improves nutrient and oxygen delivery throughout the body. Fueling the muscles with more nutrients and oxygen may improve exercise performance.


L-Norvaline exerts anti-inflammatory effects on the endothelial cells found in blood vessels and the heart. It also provides a layer of protection for the endothelium by acting as an arginase inhibitor. Additionally, l-norvaline supports nitric oxide production, which promotes vasodilation and can help reduce the pressure exerted against artery walls when pumping blood.

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